Artemisinin Combination Therapy Can Result in Clinical Failure If Oral Therapy Is Not Directly Observed
نویسندگان
چکیده
منابع مشابه
Artemisinin based combination therapy in travel medicine.
A steadily increasing number of Western travellers are exposed to malaria. Also, numbers of migrants from malarious areas are increasing. Fast and effective treatment options are needed to ensure effective malaria treatment in these groups in the future. Artemisinin combinations are well tolerated and have shown high efficacy in malaria endemic areas. Since 2001, 42 malaria endemic countries, 2...
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Artemisinin and curcumin show an additive interaction in killing Plasmodium falciparum in culture. In vivo, 3 oral doses of curcumin following a single injection of alpha,beta-arteether to Plasmodium berghei-infected mice are able to prevent recrudescence due to alpha,beta-arteether monotherapy and ensure almost 100% survival of the animals.
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drome” as the immediate cause of death when chart review clearly showed that the patient died of the complications of endstage liver disease. The inaccuracy of death certificates has been reported in the literature [18–20]. We wish to emphasize that our statement that hepatotoxicity is a limiting factor for the use of highly active antiretroviral therapy in the 1998 cohort is not meant to disco...
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1 Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America, 2 Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University Medical Center, New York, New York, United States of America, 3 Massachusetts General Hospital, Harvard Medical School, Harvard School of...
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BACKGROUND Tuberculosis (TB) requires at least six months of treatment. If treatment is incomplete, patients may not be cured and drug resistance may develop. Directly Observed Therapy (DOT) is a specific strategy, endorsed by the World Health Organization, to improve adherence by requiring health workers, community volunteers or family members to observe and record patients taking each dose. ...
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ژورنال
عنوان ژورنال: Canadian Journal of Infectious Diseases and Medical Microbiology
سال: 2013
ISSN: 1712-9532
DOI: 10.1155/2013/427910